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5-MMPA (5-Methylmethiopropamine), also sometimes called mephedrene, is a synthetic stimulant and research chemical that is chemically related to methiopropamine (MPA) and other amphetamine-type stimulants.

Although it is sold by some vendors online, 5-MMPA is intended for research purposes only and not approved for human consumption. People who use it recreationally typically seek stimulant-like effects such as increased energy, alertness, euphoria, enhanced focus, or elevated mood, similar to other stimulant drugs. However, scientific information about its effects, safety, and long-term health risks is very limited, and most evidence comes from anecdotal reports.

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